A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing.
نویسندگان
چکیده
A new approach to the chemical synthesis of oligodeoxynucleotides bearing reporter functional groups at base residues of 3'-end nucleosides is reported. Applications of the 3'-end fluorescently labelled primers for automated DNA sequencing are shown.
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ورودعنوان ژورنال:
- Nucleic acids research
دوره 25 18 شماره
صفحات -
تاریخ انتشار 1997